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KMID : 0379519990150030423
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한국독성학회지
1999 Volume.15 No. 3 p.423 ~ p.426
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Acute Subcutaneous Toxicity of Sangmosu in Rats
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Kim Dae-Young
Choi Seul-Min
Chun Sun-Ah
Park Hyun-Sun
Yoo Dong-Jun
Lee Mi-Kyung
Pae Hye-Jin
Shin Dong-Hun
Kim Hyung-Sik
Ahn Mi-Young
Kwack Seung-Jun
Park Yo-An
Jang Ja-June
Lee Byung-Moo
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Abstract
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Acute subcutaneous toxicity of Sangmosu was investigated in Sprague-Dawley rats. Seven days after administration of Sangmosu (0.078~20 ml/kg), we examined the clinical signs, mortalities, body weight changes, etc. No clinical signs and mortalities were observed in animals. Any significant change of body weights was not observed. These results suggest that LD50 value of Sangmosu was above 20 ml/kg in Sprague-Dawley rats.
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KEYWORD
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Sangmosu, Acute toxicity, LD50
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